Two years ago, the word which defeated all but a certain Kavya from Kansas was ‘laodicean’, meaning ‘lukewarm, neither hot nor cold’.
Well, maybe not quite as awesome as you’d think. She, like the other candidates, was allowed to ask the derivation of the word and to check that her pronunciation was correct when she repeated the word back to the examiner. Now I’m not saying that everyone is completely au fait (geddit?) with Greek, and ancient Greek at that, but if you separate the word into its syllables – cy mo tri chous – and you know that the way we spell the sound /k/ in words derived from Greek is very often ch (mechanic, choir, chemist), you’ve only the spelling choice between the letter s or the letter c to spell the first sound ‘s’. And, of course c is a common spelling alternative for the sound ‘s’ (city, cylinder, cell, cymbal).
I won’t say ‘simples!’ in a silly foreign voice, but it isn’t impossible.